Studying spontaneous brain activity with neuroimaging methods and mathematical modelling
Hlinka, Jaroslav (2010) Studying spontaneous brain activity with neuroimaging methods and mathematical modelling. PhD thesis, University of Nottingham.
The study of spontaneous brain activity using functional Magnetic Resonance Imaging (fMRI) is a relatively young and rapidly developing field born in the mid-nineties. So far, sufficiently solid foundations have been established, mainly in validating the neuronal origin of a significant component of observed low-frequency fluctuations in the 'resting state' fMRI signal. Nevertheless, the field is still facing several major challenges. This thesis first reviews the current state of knowledge and subsequently proceeds to present original research results that are directed towards overcoming these challenges.
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