Realising the artificial chemical cell with vesicles
Pasparakis, George (2009) Realising the artificial chemical cell with vesicles. PhD thesis, University of Nottingham.
Responsive biomedical materials span a plethora of applications in the biomedical field, from stents, hydrogels, degradable implants to drug delivery systems, and are in constant further development to give properties that ultimately improve the quality of life and prevent disease. In an effort to develop cell-interacting constructs we sought to synthesize polymers with bioresponsive and even “life-like” properties. By exploiting living polymerization techniques we aim to build self-assembled capsule-mimicking structures (i.e. vesicles) that can serve as prototype copycats of natural cell membranes. Also, we aim to establish a primitive communication platform of the artificial structures with their natural counterparts (i.e. bacterial cells) by using the “glyco-code” as a means of biochemical language.
Actions (Archive Staff Only)